Pharmaceutical Intermediate Sodium Acetate Trihydrate

Pharmaceutical Intermediate Sodium Acetate Trihydrate — High-Purity Pharma Grade Solution for Precision Synthesis

Pharmaceutical Intermediate Sodium Acetate Trihydrate (CAS No. 6131-90-4) is a commonly used acetate compound in antibiotic synthesis, chemical drug manufacture and biological drug intermediate manufacturing. Produced by Shanxi Zhaoyi Chemical Co., Ltd. — a producer with more than 30 years experience and annual capacity of 150,000 tonnes — this product is characterised by purity ≥99%, chloride ≤0.005% and heavy metals ≤0.0005%. It is made with strict batch consistency, pharmaceutical-grade packaging, and a lot of compliance paperwork to meet the high standards of today's pharmaceutical synthesis processes.

Technical Specifications

Key Product Characteristics

This sodium acetate trihydrate pharma intermediate is formulated specifically for the high-precision demands of pharmaceutical synthesis — not repurposed from industrial-grade stock.

High Purity, Low Impurity Profile

With purity ≥99% and heavy metal content controlled to ≤0.0005%, each batch meets the tight thresholds required for pharmaceutical intermediate synthesis. Chloride is controlled to ≤0.005% to minimise the possibility of undesired side reactions during downstream processing.

Regulated Moisture Level

The trihydrate form has a steady, well-defined water content. This predictability is especially important in synthesis processes where excess or changing moisture may change selectivity and impair yield. You obtain constant reaction, batch to batch.

Excellent water dispersibility and solubility

The product is easily soluble and uniformly dispersed in aqueous reaction systems. So it is very appropriate to be used as a synthetic raw material, acid-binding agent, catalyst or pH regulator in a variety of pharmaceutical intermediate processes.

Inter-Batch Consistency

Shanxi Zhaoyi's size and organised manufacturing environment - 27,000 m2 - provides a rigorous control of the process. All lots are verified against the same quality specifications so you can reproduce your synthesis findings from run to run in production.

Core Application Scenarios

As a sodium acetate trihydrate pharma intermediate, this product is applied across three major synthesis categories:

Antibiotic Intermediates

Used as acetylating agent and buffer in the synthesis of beta-lactam and other antibiotic precursors. Control of impurities is directly impacting the quality of the finished API.

Chemical Drug Intermediates

Acts as an acid scavenger and pH stabiliser in multi-step organic syntheses pathways Its low chloride level means there is no interaction with sensitive chemical pathways.

Biological Intermediates For Drugs

Suitable for preparing buffer and reaction media requiring both biological compatibility and chemical purity.

Our technical staff is here to help you find the sodium acetate trihydrate USP EP grade standards that you need for your process. They can also give you the paperwork you need.

Pharmaceutical Intermediate Sodium Acetate Trihydrate vs Other Products

Quality Control and Compliance Documentation

Sourcing a pharmaceutical sodium acetate trihydrate manufacturer means you need more than a Pharmaceutical Intermediate Sodium Acetate Trihydrate product. — you need documentation that holds up under regulatory scrutiny.

Shanxi Zhaoyi provides:

• Batch-specific Certificate of Analysis (COA)
• Material Safety Data Sheet (MSDS) in multiple languages
• Third-party testing support upon request
• Documentation aligned with pharmaceutical industry compliance requirements

All shipments are traceable. Order documentation bundles adapted to your internal QA needs or regional regulatory norms.

Certifications & Compliance

Shanxi Zhaoyi Chemical Co., Ltd. maintains internationally recognized management system certifications:

• ISO 9001 —  Quality Management System
• ISO 14001 — Environmental Management System
• ISO 45001 — Occupational Health and Safety Management System

Kosher Certification

Halal Certification (for applicable food/pharma-grade products)

The plant is open for factory audits by local and foreign clients. That's how we help you manage supply chain compliance with confidence via this transparency.

Packaging and Storage Guidelines

Proper handling preserves the integrity of the goods from our warehouse to your queue.

Store in a dry, cool and clean place with relative humidity < 65%.

Avoid contact with hazardous chemicals, oxidants and strong odours

Seal after opening and use within 24 hours to avoid moisture absorption

Shelf life 24 months unopened condition; re-inspection necessary if expired

Impact or crushing during shipment may damage packing. Do not let

Standard packaging options: 25 kilogram plastic woven bags or 1,000 kg tonne bags, appropriate for both lab-scale and bulk industrial procurement.

After-Sales and Technical Support

When you work with us, support doesn't end at shipment.

• Quality guarantee: Full return or exchange if product fails to meet synthesis requirements
• Technical response: Within 24 hours for application, dosage, and process questions
• Free samples: Small-batch samples available to verify product compatibility before committing to a full order
• Supply planning: We stock ahead based on your production schedule to prevent delays
• Complaint resolution: Response within 3 working days with actionable solutions

Our 24/7 technical consultation service means you're never waiting long for an answer during critical production windows.

FAQ

Q: What purity does your product meet?

A: Our product purity ≥99%, chloride ≤0.005%, heavy metals ≤0.0005% can fully fulfil the synthesis of pharmaceutical intermediates.

Q: Is there any literature on sodium acetate trihydrate usp ep grade?

A: Yeah. We can supply COA, MSDS and 3rd party test report. Contact us to discuss your documentation requirements to fit your regulatory environment.

Q: As a pharmaceutical sodium acetate trihydrate manufacturer, how do you ensure the homogeneity of each batch?

A: We have a 27,000 square metre facility with organised process controls and quality testing each batch. Release settings will be the same for each batch.

Q: What is the minimum order quantity, and how quickly can you deliver?

A：We maintain safety stock for standard products. Stock orders can ship within 24 hours. Custom or large-volume orders typically have a 5–7 working day lead time.

Q: What are the storage requirements after opening?

A：​​​​​​​Reseal after opening and eat within 24 hours. Keep in a tightly closed container in a cold, dry place. Store in a refrigerator. Store at <65% relative humidity. Store away from oxidising agents and other materials with which it may react.

Q: Do you support on-site plant audits?

A: Yes. We welcome audits from local and foreign clients and are able to produce the required quality and compliance paperwork in advance.

Contact Us

Ready to source reliable Pharmaceutical Intermediate Sodium Acetate Trihydrate for your production needs? Reach out to our team at sxzy@sxzhaoyi.com  — we respond within 2 hours.